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Clinical data
Trade namesArimidex, others
AHFS/Drugs.comMonograph
MedlinePlusa696018
License dataUS   FDA: Anastrozole
Pregnancy categoryUS: D (Evidence of risk) [1]
Routes of administrationBy mouth (tablets)
Drug classAromatase inhibitor; Antiestrogen
ATC codeL02BG03 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability83–85%
Protein binding40%
MetabolismLiver (85%)
Elimination half-life46.8 hours [2]
ExcretionUrine (11%)

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It is not liquid anastrozole if letrozole is secreted into breast milk. nastrozole Arimidex and letrozole Femara are liquid anastrozole aromatase inhibitors, anti-cancer medications used for treating postmenopausal women with breast cancer.respectively.

DISCLOSURE: Dr. Gray reported no conflicts of interest.

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The major circulating metabolite of anastrozole, triazole, lacks pharmacologic activity.8.

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